Enzyme-Prodrug Strategies for Cancer Therapy Rutilius Taurus Aemilianus It is demonstrated why he

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Enzyme-Prodrug Strategies for Cancer Therapy Rutilius Taurus Aemilianus It is demonstrated why heAntibody directed enzyme prodrug therapy (ADEPT) directly addresses the major problem in cancer chemotherapy its lack of selectivity. Antibody delivery combined with the amplification provided by the enzymatic activation of prodrugs enables selection to be made between tumour and normal tissue. ADEPT offers a novel field of opportunities in the therapy of systemic cancer and may be a major advance for the treatment of solid tumours. This book is the